Osteochondral allografts: state of the art.
نویسندگان
چکیده
The use of osteochondral allografts to treat focal osteochondral lesions continues to gain popularity, supported by long-term results. Clinicians must be knowledgeable concerning the possible risks of disease transmission, graft rejection, infection, and graft failure to advise the patient and obtain an informed consent. With advancing scientific and clinical research, future operative indications will likely continue to expand. A significant amount of literature regarding storage methods has recently been published; it is hoped that continued research will lead to techniques for prolonged graft storage to prevent availability concerns.
منابع مشابه
Osteochondral Allografts in the Ankle Joint
Purpose: The aim of this systematic review is to report about the clinical use of partial and total fresh osteochondral allograft in the ankle joint. The state of the art of allografts with regard to basic science, procurement and storage methods, immunogenicity, generally accepted indications and contraindications, and the rationale of the allografting procedure have been described. Methods: A...
متن کاملChondrocyte viability in press-fit cryopreserved osteochondral allografts.
The viability of chondrocytes in press-fit glycerol-preserved osteochondral allografts was compared to that in fresh autografts, after transplantation into load-bearing and non-load-bearing sites in mature sheep stifle joints. We used macroscopic grading, tonometer pen indentation testing, histology, sulfate uptake and viability as determined by confocal-microscopy to assess cartilage condition...
متن کاملComparison of fresh osteochondral autografts and allografts: a canine model.
BACKGROUND Osteochondral autografts and allografts have been widely used in the treatment of isolated grade IV articular cartilage lesions of the knee. However, the authors are not aware of any study that has prospectively compared fresh osteochondral autografts to fresh allografts with regard to imaging, biomechanical testing, and histology. HYPOTHESIS The imaging, biomechanical properties, ...
متن کاملHistopathological Changes after Transplantation of Stored Osteochondral Allografts into Articular Cartilage Lesions in Dogs
The aim of this study was to evaluate histopathological changes in the recipient site after transplantation of stored osteochondral allografts into articular cartilage defects in 8 dogs. In all dogs a single osteochondral allograft was transplanted into articular cartilage lesions. The results of the completed surgeries include a 12-month follow-up study. It was found that the stored osteochond...
متن کاملThe basic science and clinical applications of osteochondral allografts.
Indications for the use of osteochondral allografts for orthopaedic surgical applications are increasing with improved surgical techniques and advancing experience. Modern tissue banks have developed harvesting, processing, and storage methods that ensure an adequate, safe supply of grafts. Continued research is necessary to find a technique that maximizes chondrocyte viability and metabol...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Clinics in sports medicine
دوره 28 2 شماره
صفحات -
تاریخ انتشار 2009